Designs for Health SAMe
Designs for Health SAMe is a naturally occurring metabolite found in the human body as well as in plant and animal foods. It is the most active of all methyl donors and has been compared to ATP in its importance for the body.
SAMe is naturally synthesized in humans from the amino acid methionine in the presence of the cofactors B12 and folate.
SAMe is involved in the synthesis of neurotransmitters, the hormone melatonin, phospholipids, and polyamines, which control cellular growth.
It is also the source of methyl groups inside the nucleus for DNA methylation, which controls gene expression and masking of genetic damage.
These capsules provide 200 mg of SAMe along with vitamins B6, B12, and folate as 5-MTHF in order to provide cofactors for the natural conversions of SAMe to L-homocysteine and then safely to L-cysteine.
Serving Size 1 capsule
Amount Per Serving .....% Daily Value
Vitamin B-6 ... 5 mg 250%
Folate ... 100 mcg 25%
(as Quatrefolic' -5-Methyltetrahydrofolate, glucosamine salt 200 mcg)
Vitamin B-12 (as Methylcobalamin) ... 50 mcg 830%
SAMe ... 200 mg *
(as S-Adenosyl-L-Methionine Disulfate P-Toluenesulfate)
*Daily Value not established.
Microcrystalline cellulose, vegetable stearate, calcium chloride anhydrous, calcium oxide.
*These statements have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to treat, mitigate, diagnose or cure any disease.