Thorne Research Hepagen

by Thorne Research

Thorne Research Hepagen provides both canine and feline liver protection – with CurcuVET®

Because toxins in the environment can also find their way into their food and water, the liver can be a very busy organ for companion animals. Hepagen is a unique formula that combines the beneficial liver herbs milk thistle and curcumin (from turmeric) with antioxidants and other important ingredients that support normal phase I and phase II detoxification in the animal’s liver.

Healthy liver function is necessary for the activation of pyridoxine (vitamin B6). In cases where liver health is diminished, the active form of vitamin B6 – pyridoxal 5'-phosphate – is probably indicated. Hepagen provides 5 mg of active vitamin B6 per capsule. Pyridoxal 5'-phosphate is necessary because it’s a cofactor for so many enzyme reactions.

Hepagen also contains the active form of vitamin B12 – methylcobalamin – which is essential for energy production in the cells of the body. Vitamin B12 is also necessary to digest amino acids and to metabolize carbohydrates and fats. Because much of the vitamin B12 that is needed is stored in and then supplied by the liver, a properly functioning liver is essential to maintain adequate B12 levels.

Dimethylglycine (DMG) – a derivative of the simplest amino acid, glycine – is a building block for many important substances, including methionine. Methionine, an essential sulfur-containing amino acid necessary for phase II detoxification, also helps metabolize fats and is a necessary precursor to cysteine and taurine synthesis.

N-acetylcysteine (NAC) is composed of the amino acid cysteine and a sulfhydryl group, which enables NAC to interact with disulfide bonds. NAC serves as a precursor for the synthesis of glutathione, which is essential for multiple liver detoxification processes.

Silybum marianum(milk thistle) contains several flavonolignans that are collectively referred to as silymarin. The antioxidant activity of silymarin helps to stabilize hepatocyte membranes, neutralize free radicals, and maintain liver glutathione levels.

Suggested Use: Cats: 1/2 capsule daily
                        Dogs: 1 capsule per 25 lbs. body weight daily


Active Ingredients Per Capsule:

L-Methionine ......100 mg.

N-Acetyl-L-Cysteine..... 100 mg.

Dimethylglycine (Hydrochloride)...... 50 mg.

Milk Thistle extract (fruit) (Silybum marianum) ......50 mg.

Curcumin Phytosome (Curcuma longa extract (root) / Phospholipid complex from Sunflower) (CurcuVET®) .....50 mg.

Pyridoxal 5'-Phosphate (Vitamin B6) .....5 mg.

Methylcobalamin (Vitamin B12)...... 50 mcg.

Other Ingredients: Hypromellose (derived from cellulose) capsule, Calcium Laurate, Silicon Dioxide.

For use in cats and dogs only.
Recommended for promoting hepatic support.

Warnings For animal use only.

Keep out of the reach of children and animals. In case of accidental overdose, contact a health professional immediately.

* These statements have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to treat, mitigate, diagnose or cure any disease.

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